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Associate Professor

    YANG Wenchao

    Chinese Version  (中文版)

    Resume

    EDUCATION

    Post Doc.                  Pharmaceutical science, University of Kentucky (2010)

    Ph.D.                        Chemical Biology, CCNU (June2009)

    Exchanged Ph.D.     Pharmaceutical science, University of Kentucky (2005-2009)

    B.A.                         Chemical Education,CCNU (June2003).

    POSITIONS

    2014-2015 Hong Kong Scholar, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University

    2012-present Associate Professor, College of Chemistry, CCNU

    2009 Assistant Professor, College of Chemistry, CCNU.

    Research Fields and Interests

    1) Bioanalytical chemistry

    2) Chemical biological study of target enzyme

    Selected Publications

    1) Sun Q.; Yang S. H; Wu L.; Dong Q. J.; Yang, W. C.*; Yang, G. F.* Detection of intracellular selenol-containing molecules using afluorescent probe with near-Zero background signal. Anal. Chem. 2016, 88, 6084-6091.

    2) Sun Q.; Yang S. H; Wu L.; Yang, W. C.*; Yang, G. F.* A Highly Sensitive and Selective Fluorescent Probe for Thiophenol Designed viaa Twist-Blockage Strategy. Anal. Chem. 2016, 88, 2266-2272.

    3) Xu, Y. L.; Lin, H. Y.; Ruan, X.; Yang, S. G.; Hao, G. F.; Yang, W. C. *; Yang, G. F.* Synthesis and bioevaluation ofpyrazole-benzimidazolone hybrids as novel human 4-Hydroxyphenylpyruvate dioxygenase inhibitors. Eur. J. Med. Chem. 2015, 92, 427-438.

    4) Wang, D. W.; Lin, H. Y.; Cao, R. J.; Ming, Z. Z.; Chen T.; Hao, G. F.; Yang, W. C.*; Yang, G. F.* Design, synthesis and herbicidal activity of novel quinazoline-2, 4-diones as 4-hydroxyphenylpyruvate dioxygenaseinhibitors. Pest. Manag. Sci. 2015, doi:10.1002/ps. 3894.

    5) Wang, D. W.; Lin, H. Y.; Cao, R. J.; Yang, S. G.; Chen, Q.; Hao, G. F.; Yang, W. C. *; Yang, G. F.* Synthesis and Herbicidal Evaluation of Triketone-Containing Quinazoline-2, 4-diones. J. Agric. Food Chem. 2014, 62, 11786-11796.

    6) Li, J.; Zhang, C. F.; Yang, S. H.; Yang, W. C.*; Yang, G. F.* Acoumarin-based fluorescent probe for selective and sensitive detection ofthiophenols and its application. Anal. Chem.2 014, 86, 3037-3042.

    7) Sun Q.; Li J.; Liu W. N.; Dong Q. J.; Yang, W. C.*; Yang, G. F.* Non-peptide-based fluorogenic small-molecule probe for elastase. Anal. Chem. 2013, 85, 11304-11311.

    8) Li, J.; Zhang, C. F.; Ming, Z. Z.; Hao, G. F.; Yang, W. C.*; Yang, G. F.* Coumarin-based novel fluorescent zinc ion probe in aqueous solution. Tetrahedron 2013, 69, 4743-4748.

    9) Peng, D. Y.; Sun, Q.; Zhu, X. L.; Lin, H. Y.; Chen, Q.; Yang, W. C.*; Yang, G. F.* Design, Synthesis, and Bioevaluation of Benzamides: Novel Acetylcholinesterase Inhibitors with Multi-functions on Butylcholinesterase, Aβ Aggregation, and β-Secretase. Bioorg. Med. Chem. 2012, 20, 6739-6750.

    10) Yang, W. C.; Li, H.; Wang, F.; Zhu, X. L.; Yang, G. F. * Rieske Iron–Sulfur Protein of the Cytochromebc1 Complex: A Potential Target for Fungicide Discovery. Chembiochem 2012, 134, 1542-1551.

    Honors and Awards

    2015 Best Oral Presentation Winner in Hong Kong Scholar Annual Symposium

    2014 Hong Kong Scholar Fellow

    2012 Excellent Poster Award of the 4th “Pesticide and Environmental Security” International Academic Forum, the 5thPan-Pacific Pesticide Scientific Conference & the 8th “Plant Chemical Protection and Global Regulation Integration” International Forum.     

    2012 2nd award for teaching at College of Chemistry of CCNU

    2004 3rd award of the CCNU English Speech Competition of Non-English Majors

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