个人信息
姓名:郭瑞
学历:博士
职称:研究员
E-mail:ruiguo@ccnu.edu.cn
课题组网站:https://www.x-mol.com/groups/Zhang_Guozhu
教育与研究经历
郭瑞,男,1989年出生于山东寿光,现任bevictor伟德官网研究员
2023年3月-至今,bevictor伟德官网,bevictor伟德官网,研究员,硕士生导师
2020年12月-2023年3月,中国科学院上海有机化学研究所,助理研究员
2018年9月-2020年9月,美国匹兹堡大学,化学系,博士后,合作导师:Prof. Yiming Wang
2015年9月-2018年6月,中国科学院上海有机化学研究所,博士,导师:张国柱研究员
2012年9月-2015年6月,兰州大学,化学化工学院, 硕士,导师:翟宏斌教授
2008年9月-2012年6月,中国海洋大学,医药学院,学士
研究领域与兴趣
1. 过渡金属催化有机合成方法学
2. 自由基介导的碳氢键官能团化反应
3. 有机氟化学
4. 生物活性分子的合成与功能优化
承担项目与课题信息
1. 国家自然科学基金青年项目,2024.01-2026.12,主持
2. 华中师范大学高层次人才启动经费,2023.03-2028.03,主持
学术成果(代表性论文)
1. J. Li#, S. Li#, G.-H. Cui, K. Yuan, C. Wang, C. Yang, G. Zhang*, R. Guo*, Photoinduced Copper-Catalyzed Regio- and Enantioselective Alkynylation of Epoxides. ACS Catal. 2024, 14, 7553–7561. (# contributed equally)
2. K.-Q. Tian#, S.-J. Zhang#, J. Zhao, G.-Y. Duan, Q.-L. Wang, G.-H. Cui, R. Guo*, H.-S. Li*, Regio- and Diastereoselective Highly Strained Alkylidenecyclobutane Isomerization/Hydroacylation: Synthesis of Multisubstituted Cyclobutanes with Consecutive Stereocenters. ACS Catal. 2024, 14, 1505−1513. (# contributed equally)
3. J. Zheng, H. Zhang, S. Kong, Y. Ma, Q. Du, B. Yi, G. Zhang*, and R. Guo*, Copper-Catalyzed General and Selective α-C(sp3)–H Silylation of Amides via 1,5-Hydrogen Atom Transfer. ACS Catal. 2024, 14, 1725–1732.
4. J. Lu#, M. Zhang#, X. Zheng, P. Shen, Y. Xu, Q. Zhang, Y. Tang, G. Zhang*, and R. Guo*, Rhodium(I)-Catalyzed Enantioselective Ring-Opening and Isomerization of Cyclobutanols through a (Z)-Unsaturated Ketone Intermediate. Org. Lett. 2023, 25, 5151–5156. (# contributed equally)
5. Rui Guo, Chao Shu*, Guozhu Zhang*, “Photoinduced Metal-free α-C–H Borylation of Aliphatic Amines”, Chem, 2022, 8, 2902-2904. (Previews)
6. Rui Guo‡, Haijing Xiao‡, Sijia Li, Yixin Luo, Jiahui Bai, Mengzhen Zhang, Xiaotian Qi*, Yinlong Guo*, Guozhu Zhang*, “Photoinduced Copper-Catalyzed Asymmetric C(sp3)-H Alkynylation of Cyclic Amines by Intramolecular 1,5-Hydrogen Atom Transfer”, Angew. Chem. Int. Ed., 2022, 61, e202208232. (‡: contributed equally)
7. Rui Guo‡, Xiaotian Qi‡, Hengye Xiang, Paul Geaneotes, Ruihan Wang, Peng Liu*and Yi-Ming Wang*, “Stereodivergent Alkyne Hydrofluorination Using Protic Tetrafluoroborates as Tunable Reagents” Angew. Chem. Int. Ed., 2020, 59, 16651−16660. (‡: contributed equally)
8. Rui Guo, Xueling Mo, Guozhu Zhang*, “Synthesis of 2-(2-Oxo-2-phenylethyl)cyclopentanone by Rhodium-Catalyzed Tandem Alkynyl Cyclobutanols Hydroacylation and Semipinacol Rearrangement” Org. Lett., 2019, 21, 1263−1267.
9. Rui Guo and Guozhu Zhang*, “Expedient Synthesis of 1,5-Diketones by Rhodium-Catalyzed Hydroacylation Enabled by C−C Bond Cleavage” J. Am. Chem. Soc., 2017, 139, 12891−12894.
10. Rui Guo‡, Xinxin Zheng‡, Dayong Zhang*, Guozhu Zhang*, “Rhodium(I)-catalyzed stereoselective [4+2] cycloaddition of oxetanols with alkynes through C(sp3)–C(sp3) bond cleavage” Chem. Sci., 2017, 8, 3002−3006. (‡: contributed equally)
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